We are a computational laboratory (BIG.CAS page) in the CAS Key Laboratory of Genomic and Precision Medicine at Beijing Institute of Genomics, Chinese Academy of Sciences.
Computing the Role of Alternative Splicing in Cancer
Mutations in the RNA splicing factor SF3B1 promote tumorigenesis through MYC stabilization
Pan-cancer analysis identifies SUGP1 mutations recapitulate mutant SF3B1 mis-splicing
Genomic characterization of HIV-associated plasmablastic lymphoma
Pharmacogenomic landscape of patient-derived tumor cells informs precision therapy
Comprehensive characterisation of lncRNAs in pancreatic ductal adenocarcinoma
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